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Thread: Erectile dysfunction: side effects of drugs

  1. #1

    Erectile dysfunction: side effects of drugs

    Many reassuring studies on the tolerance of these drugs

    The drugs that induce erection, which appeared on the market in 1998, are now widely used throughout the world. Initial doubts about their tolerance have since given place to a great confidence of the medical profession, due to the numerous observational studies carried out.

    Moderate side effects that do not stop treatment

    Are side effects frequent? What are they? Are they dangerous? Do they stop treatment? How to minimize them at best? Recent answers from scientists.

    Vascular, digestive or musculoskeletal adverse reactions

    For dozen years, doctors have effective drugs against erectile dysfunction. These include sildenafil (Viagra ®), tadalafil (Cialis ®) and vardenafil (Levitra ®). These are all three inhibitors of the phosphodiesterase PDE5, an enzyme that normally degrades the substances emitted in the case of excitation and which allow the erection (see our animation: "The mechanism of the erection in images"). Br>

    Caution in case of serious or recent cardiovascular problem

    This marketing was preceded by numerous studies, first on the animal and then on the man. Since their commercialization, new studies have been carried out to study the impact of these drugs in different circumstances: men more or less old, origin of erectile dysfunction, cardiovascular history, etc.

    The importance of good use

    While initially patients and doctors were reluctant to use these products, these various scientific works made it possible to check the good tolerance of these medicines, provided that they respect the contraindications. This explains why their prescription has now become medical, which has revolutionized the management of erectile dysfunction.

    Despite this paradigm shift, the notices of the various medicines prescribed by the doctor in the event of erectile dysfunction can however still make users doubtful. They contain a long list of adverse reactions. But this is also the case with most medicines, since manufacturers are required to list all possible adverse reactions, even those that are minimal, rare or triggered only under very special circumstances.

    In practice, the side effects of these treatments are therefore generally "mild to moderate and transient" 1, according to Dr. Alexander Tsertsvadze and his colleagues at the University of Ottawa, who recently analyzed 222 studies, including 161 rigorous studies Relating to one or other of these three products (or comparing all three).

    Moreover, the occurrence of side effects does not usually lead to discontinuation of treatment: only 0.5 to 3.8% (according to the studies) of users have stopped taking one of these three drugs Because of side effects 1!

    The most common side effects are headache (10 to 14% of users depending on the product), facial flush (4 to 11%) and stomach pain (4 to 7% ). Musculoskeletal pain, back pain, blurred vision or a stuffy nose can also occur. In general, the risk of "serious adverse effects", cardiovascular or other effects, under vardenafil, tadalafil or sildenafil, is 1% on average, a similar figure when taking a placebo 1. Br>

    Although the risk of a "serious" side effect is mild, it should be taken into account, especially in people with a heavy cardiac history. As a result, these three drugs are contraindicated for recent myocardial infarction (less than 3 months), stroke less than 6 months, unstable angina pectoris, severe heart failure, Uncontrolled rhythm or hypertension disorders 2.

    In case of a notable cardiovascular history, it is therefore the attending physician who can judge the relevance of this treatment. In practice, taking such medicines is possible in case of "moderate or intermediate" cardiac disorders. 3.

    Other contraindications are concomitant use of nitrates (risk of hypotension) and hypersensitivity (allergy) to the molecule (rare).

    Other factors that may increase the risk of adverse events include misuse: take a double or triple dose of the one prescribed, associate it with other undeclared products, etc.

    In addition, mailboxes have been flooded with spams for a few years with erectile inducer drugs at unbeatable prices. However, these are often false ones containing no active ingredient or incorrectly dosed, sometimes dangerous, cut with other substances responsible for undesirable effects (see our article: "Cialis ®, Viagra ®: beware counterfeit! "). Moreover, in the United States, the purchase and sale of medicines on the Internet or by correspondence are illegal and strictly prohibited.

    In conclusion, erectile inducer drugs have been used for over 10 years worldwide without major side effects listed. The adverse effects observed by some of the users are generally minor and transient, but in more than 95% of cases the treatment is not continued. It is important to consult your doctor for a prescription adapted to the disorders, and to buy the medicine prescribed in pharmacy.

    Available since 1988, treatments for erectile dysfunction are now widely prescribed. How did they change your sexuality ?, Participate in our survey by clicking here.

    1 - "Oral phosphodiesterase-5 inhibitors and hormonal treatments for erectile dysfunction: Tsertsvadze A et al., Annals of Internal Medicine, November 2009, 3,151 (9): 650-61, available online 2 - RCP of Viagra ®, Cialis ® and Levitra ®, Vidal 2010; 3 - "Erectile dysfunction and heart failure: the role of phosphodiesterase type 5 inhibitors", Al - Ameri H, Kloner RA International Journal of Impotence Research , May-June 2009,, 21 (3): 149-57, available online

  2. #2

    Re: Erectile dysfunction: side effects of drugs

    Tadapox pills (ED tablets) are very important in the person with impotence. But these pills are very harmful. These pills are very effective and strong medicines. To use more of this pill can prove harmful to the body. like as headache, Body aches and pains, Dizziness, Flushes etc.

  3. #3

    Re: Erectile dysfunction: side effects of drugs

    erectile dysfunction is quite shameful, I read in an article here that should be treated as a couple not only man and can be caused by stress

  4. #4

    Re: Erectile dysfunction: side effects of drugs

    Sildigra 100mg (sildenafil citrate 100mg) are very vital medicine for suffer from ed life. in impotence. These pills are very effective and strong medicines. Don't uses two pills together proven harmful our body. like as headache, Body aches and pains, Dizziness, Flushes etc.

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