It is a rare disease of the skin characterized by pigmented, blackish, verrucous or papillomatous plaques, traced in furrows and symmetrically sitting on the armpits and groins.

Acanthosis nigricans may appear at birth in the context of a nævic or familial disease.

The appearance of an acanthosis nigricans rapidly progressive towards 40 years, especially if it is associated with an alteration of the general state, must make seek by the doctor a digestive cancer (stomach) in the framework of a paraneoplastic syndrome. Code>

Acanthosis nigricans can also be seen during endocrine disorders (obesity, hypercortisolism).