Three minutes of happiness!

Before sketching a mocking smile, take a look at these figures: between 21 and 33% of men would face a problem of premature ejaculation. As with erectile dysfunction, medications are now available. Discover the solutions to this intimate problem.

A drug marketed since April 2013

Under the coordination of Pr. Pryor of the University of Minnesota, the results of two large trials to evaluate the efficacy of a new molecule to treat premature ejaculation have been published in the prestigious magazine The Lancet 1. And the Results are promising!

More than 2,600 men were recruited to participate in this study, all ejaculating on average less than one minute after penetration. A delay induced in the couple an obvious frustration ... divided into three groups, these "patients" had to take one to three hours before the relationship either a placebo, 30 mg of dapoxetine or 60 mg of dapoxetine. For three months with at least 6 relationships per month, couples should note the time between penetration and ejaculation ... If the methodology of the study is not particularly exciting, the results are significantly more! Code>

After 12 weeks, the mean sexual intercourse time was 1.75 minutes for the placebo group, 2.78 minutes for the 30 mg group and 3.32 minutes for the 60 mg group of dapoxetine. Not yet enough to enter the Guiness Book but a clear progress according to the authors of the study. "This molecule also improves patients' perception of ejaculation control, sexual satisfaction and general perception of their condition." The partners also benefit from improved sexual satisfaction, "Dr. Pryor concluded. Note however that this compound causes side effects not erotic: nausea, diarrhea, headache ...

Dapoxetine belongs to the class of selective serotonin reuptake inhibitors, a family of antidepressants. It has been known for several years that these drugs can lengthen the ejaculation period. The mechanisms involved have recently been highlighted by Dutch researchers.2 In premature ejaculation victims, serotonin receptors located in the central nervous system are less reactive to this neurotransmitter. This lower sensitivity does not allow the man to delay his ejaculation. Inhibitors of serotonin reuptake lead to an overabundance of serotonin and thus a delayed effect on ejaculation.


Since April 2013, dapoxetine (marketed under the name PRILIGY ®) has received a marketing authorization for the treatment of premature ejaculation in men aged 18 to 64 years.
Today, the management of premature ejaculation rests on two complementary approaches: behavioral and psychological therapies on the one hand and the use of drug treatments. It is a priori that the combination of the two approaches allows optimal processing.

Sources

1 - Lancet 2006,368: 929-937; 2 - Behavioral Brain Research 92 (1998) 111-118; 3 - Questions and answers about Priligy (dapoxetine, tablets 30 mg and 60 mg) - Result from a procedure under Article 29 of Directive 2001/83 / EC as amended - EMA - (document available on line) 4 - It is indicated in case of ejaculation occurring in less than two minutes after penetration, which permanently Or recurrent, occurs with minimal sexual stimulation before, during or shortly after penetration, and before the patient so wishes, significant personal suffering or interpersonal difficulties associated with premature ejaculation, Ejaculation and history of premature ejaculation in most reports over the past 6 months.