Treatment of bronchial secretion disorders, particularly in acute bronchitis: acute bronchitis and acute episode of chronic bronchopneumonia

Dosage

Adults and children over 7 years of age, 600 mg daily in 3 doses, ie 1 tablet 3 times a day,
Children 2 to 7 years of age: 400 mg per day in 2 divided doses, ie 1 tablet twice daily,
The duration of the treatment will not exceed 8 to 10 days without medical notice.

Mode of administration

Oral use.

Dissolve the tablet in a little water.

Pharmacotherapeutic group: MUCOLYTICS

(R: Respiratory System)

Acetylcysteine ​​is a mucolytic mucoformer. It exerts its action on the gel phase of the mucus, presumably by breaking the bridges, disulfides of the glycoproteins, and thus promotes the expectoration.
Not applicable.

· History of hypersensitivity to any of the constituents

· Infant (under 2 years of age) (see Warnings and Precautions for Use).
Special warnings

The productive coughs, which represent a fundamental element of broncho-pulmonary defense, must be respected.

The association of mucomodifiers, bronchodilators with antitussives and / or substances, drying (atropinic) secretions is irrational

Mucolytics can induce bronchial overcrowding in infants. Indeed, its capacity for draining bronchial mucus is limited, due to the physiological peculiarities of its respiratory tree. Therefore, they should not be used in infants (see sections Contraindications and adverse effects)

Treatment should be re-evaluated in the event of persistence or aggravation of symptoms or pathology.

This medicinal product contains sorbitol and is not recommended for use in patients with fructose intolerance (rare hereditary disease)

This medicine contains lactose and is not recommended for use in patients with galactose intolerance, Lapp lactase deficiency or malabsorption syndrome, glucose or galactose (hereditary or rare diseases). Br>

Precautions for use

Caution is advised in patients with peptic ulcers.

This medication contains sodium, which contains 114.9 mg sodium per tablet. To be taken into account in patients following a strict diet.

Not applicable.

Not applicable.

No cases of overdose have been reported.

Pregnancy

There is no reliable evidence of teratogenesis in animals.

In the clinic, no particular malformative or fetotoxic effect has appeared to date. However, monitoring of pregnancies exposed to acetylcysteine ​​is insufficient to exclude any risk.

Therefore, as a precautionary measure, it is preferable not to use acetylcysteine ​​during pregnancy.


There is no data concerning the passage of acetylcysteine ​​in breast milk.

However, due to its low toxicity, the potential risks to the child appear negligible when treated with this medication, therefore breastfeeding is possible.

· Risk of bronchial over-crowding, especially in the infant and in some patients who are incapable of expectoration, effective (see sections Contraindications and Warnings and Precautions). >

Allergic skin reactions such as pruritus, erythematous rash, urticaria and angioedema

· Possibility of phenomena, intestinal digestive (gastralgia, nausea, diarrhea).

It is then advisable to reduce the dose.

Treatment of bronchial secretion disorders, particularly in acute bronchitis: acute bronchitis and acute episode of chronic bronchopneumonia