Adult: 1 to 2 tablets 3 times a day.

The duration of the treatment should not exceed 5 days without medical advice.

In the absence of improvement at the end of 5 days of treatment, it is necessary to take a medical opinion.

Mode of administration

Oral use.

Swallow the tablet with a glass of water

The productive coughs, which represent a fundamental element of broncho-pulmonary defense, must be respected.

The association of a mucolytic with a cough suppressant and / or with a substance which dehydrates (atropinic) secretions is irrational.
Very rare cases of severe skin lesions of the Stevens-Johnson syndrome or Lyell syndrome have been reported in patients treated with bromhexine. In most cases, these reactions may be explained by the severity of the disease, underlying or by concomitant treatments, and because of co-prescribed treatments, accountability remains questionable. Of skin lesions or mucous membranes during treatment should lead, as a precautionary measure, to discontinue treatment with bromhexin.

Bromhexin precipitates in a solution of pH greater than 6. This tablet should not be dissolved in a solute.

No specific symptoms of overdose have been reported to date in humans.
In case of overdose the treatment will be symptomatic.


Studies in animals have not shown any direct or indirect effects on pregnancy, embryonic or fetal development, postnatal development or development (see section 4.4 Preclinical safety data) .

There is little clinical data on the use of bromhexin during pregnancy

As a precautionary measure, it is preferable not to use Bisolvon during pregnancy.

There are no data on the excretion of bromhexin in milk. The use of Bisolvon during lactation should be based on the benefit of breastfeeding for the child and on the basis of the therapeutic benefit for the mother
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Immune system disorders, skin and subcutaneous tissue disorders

Anaphylactic reaction including anaphylactic shock, angioedema, rash, urticaria, pruritus and other hypersensitivity reactions

Gastrointestinal disorders

Nausea, vomiting, diarrhea and upper abdominal pain including gastralgia

Respiratory, thoracic and mediastinal disorders

Risk of increased congestion, bronchitis in some patients unable to expectorate, effective