Capsule brown / yellow, marked “RX 655” in ink, black on the head and body of the capsule, containing a white to off-white powder.
Warnings, special

· The occurrence of any allergic manifestation requires cessation, treatment, and implementation of a treatment, adapted.

· Allergy to penicillins is crossed with allergy to cephalosporins in 5 to 10% of cases This leads to the proscription of penicillins when the subject is a known allergic to cephalosporins. >

The occurrence of generalized, febrile erythema at the onset of treatment with pustules should give rise to suspected acute exanthematous pustulosis (see section 4.4), discontinuation of treatment and Contraindicates any new, administration of amoxicillin alone or in combination.

Precautions for use

· As with all beta-lactams, regularly check the blood formula in case of administration of high doses of amoxicillin

The administration of high doses of beta-lactams in patients with renal insufficiency or in patients with predisposing factors such as a history of seizures, epilepsy, or treatment with meningeal disease may exceptionally lead to convulsions. Code>
· In case of renal insufficiency, adjust the dose according to creatinine clearance or serum creatinine (see Dosage and Mode of Administration).

· The existence of a weak urinary flow is a risk factor for the occurrence of crystalluria.

· When administering high doses of amoxicillin, adequate water intake should be provided to reduce the risk of crystalluria

· The use of capsules is contraindicated in children under 6 years of age because it can lead to a false route.

· Treatment of Lyme Disease: Jarish-Herxheimer reactions may occur.

Paraclinical examinations

Impact on biological parameters

A positivity of the direct Coombs test was obtained during treatment with beta-lactams. This could also occur in subjects treated with amoxicillin.

A, very high concentrations, amoxicillin tends to

· Decrease the results of blood glucose measurements

· Interferes in the determinations of the total serum protein by color reaction

· Give a false positive color reaction in the glycosuria assays by the colorimetric semi-quantitative method