Treatment of onychomycoses, subalucleal distal and lateral, moderate, caused by dermatophytes, yeasts or molds, not touching more than two nails, in adults.

Apply AMOROLFINE RANBAXY to the affected nails at once a week.

To apply the varnish, follow carefully the following recommendations

For packaging without accessories

A. Before the first application of AMOROLFINE RANBAXY, thoroughly clean the nails. Remove all traces of residual varnish with a solvent, file with a file the surface of the nail (especially the affected area), as completely as possible. Take the precaution of not filing peri-nail skin.

B. Clean the surface of the nail and degrease a means of a compress or a tissue impregnated with solvent

C. Apply the varnish using one of the reusable spatulas on the entire nail. Clean the spatula, reusable between each passage from one nail to the other with a compress or fabric impregnated with a solvent, in order to avoid contamination of the varnish. Do not wipe the spatula on the edge of the bottle.

D. It is important to thoroughly clean the spatula with a compress or a cloth impregnated with a solvent after each application before re-using it for another nail in order to avoid contamination of the varnish.

E. If varnish has been deposited on the exterior of the stopper during handling, it is important to clean it with a compress or fabric impregnated with solvent, Avoid applying this varnish to the skin

F. Re-seal the bottle.

Repeat: all of the above operations for each nail reaches

After each use of AMOROLFINE RANBAXY, it is important to wash your hands, but when applied on the nails of the hands, it is necessary to wait for the complete drying of the varnish before

The treatment must be carried out without interruption until regeneration, complete the nail.

The duration of the treatment is generally 6 months for the nails of the hands and 9 months, and for the nails of the feet (it depends mainly on the intensity, the location of the infection and the height of the nail, Affection of the nail).

After 3 months of use in the absence of improvement a doctor should be consulted.
Instructions, special

· Do not reuse nail files for nails, healthy

Before each new application, remove residual varnish, file, if necessary, the affected nails and, in any case, clean them with a compress or a cloth, impregnated with solvent. >

· When handling organic solvents (white spirit, diluents, etc.), it is necessary to wear gloves, impermeable to protect the layer of varnish, AMOROLFINE RANBAXY on the nails
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For packaging with accessories

A. Before the first application of AMOROLFINE RANBAXY, thoroughly clean the nails. Remove all traces of residual varnish with a solvent, file with a file the surface of the nail (especially the affected area), as completely as possible. Take the precaution of not filing peri-nail skin.

B. Clean the surface of the nail and degrease one of the cleaning wipes provided.

C. Apply the varnish using one of the reusable spatulas on the entire nail. Clean the spatula, reusable between each passage from one nail to the other with one of the cleaning wipes supplied, in order to avoid contamination of the varnish. Do not wipe the spatula on the edge of the bottle.

D. It is important to thoroughly clean the spatula with one of the cleaning wipes supplied after each application before re-using it for another nail to avoid contamination of the varnish. >

E. If varnish has been applied to the exterior of the stopper during handling, it is important to clean it with one of the cleaning wipes provided to avoid Varnish on the skin

F. Re-seal the bottle.

Repeat: all of the above operations for each nail reaches

After each use of AMOROLFINE RANBAXY, it is important to wash your hands, but when applied on the nails of the hands, it is necessary to wait for the complete drying of the varnish before

The treatment must be carried out without interruption until regeneration, complete the nail.

The duration of the treatment is generally 6 months for the nails of the hands and 9 months, and for the nails of the feet (it depends mainly on the intensity, the location of the infection and the height of the nail, Affection of the nail).

After 3 months of use in the absence of improvement a doctor should be consulted.
Instructions, special

· Do not reuse nail files for nails, healthy

Before each new application, remove residual varnish, file, if necessary, the affected nails and, in any case, clean them with one of the cleaning wipes. >

· When handling organic solvents (white spirit, diluents, etc.), it is necessary to wear gloves, impermeable to protect the layer of varnish, AMOROLFINE RANBAXY on the nails
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OTHER ANTIFUNGALS FOR USE, TOPICAL, ATC Code: D01AE16.

AMOROLFINE RANBAXY is an antimycotic, topical. The active ingredient, amorolfine, derived from morpholine, belongs to a new chemical class of antimycotics. Its fungistatic and fungicidal effect is based on an alteration of the cell membrane, fungal directed mainly on biosynthesis, sterols.

The ergosterol content is reduced. An accumulation of atypical sterols, leads to morphological changes of the membranes and cellular organelles that cause the death of the fungal cell

Amorolphin has a broad antimycotic spectrum. It is very effective against the usual or occasional agents of onychomycoses

· Yeasts

O Candida albicans and other species of Candida

· Dermatophytes

Trichophyton rubrum, Trichophyton interdigitalis and Trichophyton mentagrophytes, other species of Trichophyton

O Epidermophyton floccosum

O Mycrosporum.

· Molds

O; Scopulariopsis.

· The dematies (black mushrooms)

Hendersonula, Alternaria, Cladosporium.

· Not sensitive species

Aspergillus, Fusarium, mucorales.

Not applicable.

History of allergy to any of the components

Special warnings

Avoid contact with AMOROLFINE RANBAXY with eyes, ears or mucous membranes.
AMOROLFINE RANBAXY should be used with caution in patients with pathologies predisposing to onychopathies (disorders, peripheral circulatory disorders, diabetes, diseases, immune system) as well as in patients with severe nail or nail dystrophy; Damaged (more than two-thirds of the nail plate is reached). In such cases systemic treatment should be considered.


Precautions for use

In the absence of data, the use of AMOROLFINE RANBAXY is not recommended, in patients