· Hypertension, arterial This dosage is particularly suitable for renal insufficiency, in which the dosage should be adjusted to the degree of renal insufficiency.
· Arrhythmias, supraventricular

O tachycardia, supraventricular paroxysmal (in preventive or curative treatment)

O fibrillation or flutter, in the event of inadequate response to digitalis, in maximal doses and in cases where digitalises are contraindicated or have an unfavorable benefit / risk ratio. >

· Ventricular arrhythmias

O ventricular extrasystoles (preventive or curative treatment) in the case of extrasystoles, resulting from an increase in activity, sympathetic
Ventricular tachycardia and ventricular fibrillation (preventive treatment), especially when the ventricular abnormality results from significant sympathetic activity.

Hypertension, arterial

The recommended dosage is 100 mg per day in one dose (ie 2 50 mg tablets). However, in cases of severe hypertension, a higher dosage may be required. >

The association with other therapeutic antihypertensives, eg diuretics, is possible.

Disorders of rhythm, after control of rhythm disorders by atenolol administered intravenously (if indicated), atenolol is administered orally and the recommended maintenance dose is 50 to 100 mg / day .

In the case of renal insufficiency, the dose is adjusted to the values ​​of serum creatinine or creatinine clearance according to the table below

Serum creatinine

Clearance of creatinine (Cl CR) (ml / min / 1.73 m 2)
Dosage

Mg / l

Mmol / l



As a result, beta-blockers, under normal conditions of use, may be prescribed during pregnancy if necessary. Careful monitoring of the newborn (heart rate and blood glucose during the first 3 to 5 days of life) should be recommended during treatment until delivery,
< Br>

Breastfeeding

Beta-blockers are excreted in the milk (see section "Pharmacokinetic properties").
The risk of occurrence of hypoglycemia and bradycardia has not been evaluated. Therefore, as a precaution, it should be avoided: in breastfeeding women

At the clinical level

The most frequently reported

· Asthenia

· Cooling of the ends

· Bradycardia, severe if necessary

· Digestive disorders (gastralgia, nausea, vomiting)

· Impotence.

Much more rarely

· Decreased conduction, atrioventricular or intensification of a block, existing atrio-ventricular

· Heart failure

· Blood pressure drop

· Bronchospasm

· Hypoglycaemia

· Raynaud's syndrome

· Aggravation of an existing intermittent claudication

· Various manifestations, skin including psoriasiform eruptions.

Biologically speaking

In rare cases, the appearance of antinuclear antibodies accompanied only by exceptional clinical manifestations in the form of lupus syndrome and which led to discontinuation of treatment.

Exceptional elevations, liver transaminases (as well as some cases of intrahepatic cholestasis).

This dose is particularly suitable for patients with renal insufficiency in whom the dosage should be adjusted to the degree of renal insufficiency Arrhythmias supraventricular o tachycardia supraventricular paroxysmal (as a preventive treatment Or curative) o fibrillation or flutter, auricular in the event of inadequate response to digitalis, maximal doses and in cases where digitalises are contraindicated or report unfavorable benefit / risk ventricular arrhythmias o (Preventive or curative treatment) in the case of extrasystoles, resulting from increased activity, sympathetic, ventricular tachycardia and ventricular fibrillation (preventive treatment), particularly when the ventricular abnormality is the result of An important sympathetic activity.